how could I erase ablock from my drawing where this drawing very large ,contains many blocks.....I know the block name but couldnot determine where is it im my dwg...I would like to erase it....

See the samples in the tip:
http://www.cadforum.cz/cadforum_en/selecting-objects-by-name-tip7082
 

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Type “pu” or “purge” enter. 
You will be able to delete your block. 
You must have it exploded or deleted from the drawing first.

You can also use the "qselect" and "filter"commands.