How can I enter  gps points if they enter  in 2 different quadrants in my case are 12R and 13R.I will appreciate all your help. 

What program are you using?

I'm not using a program especially when entry points do using UTM coordinates, had not had problems because they always entered data from the 13R quadrant, but today I had to enter data from both the 12R quadrant as the 13R points 12R are placed very far distances from where they should be, I think should change the coordinate origin in the drawing and I did but I must be doing something wrong or I'm not putting well the new origin.

I meant are you trying to do this is plain AutoCAD or some other program like Civil 3D?