AutoCAD 2008 doesn't start correctly a DWG file opened from a Windows file manager by doubleclick - it displays a message: "Windows cannot find '*.dwg'. Make sure you typed the name correctly, and then try again. To search for a file, click the Start button, and then click Search."
The problem is probably caused by a collision of the 2008-version launch program AcLauncher.exe and previous versions of AutoCAD. Either ignore the message (confirm by OK, AutoCAD opens the file), or associate the .DWG files directly with the AutoCAD 2008 application (acad.exe, acadlt.exe), or run (merge) the following .REG file, which fixes the wrong DWG associations in the Registry:
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