yes, once you create the viewport and scale it to whatever scale needed than simply select the viewport and lock it in the properties menu.  it should not effect it at all once other viewports are created.

Hey Everybody

I have a 3d object located in model space and have opened up a view port in paper space to view the object. Now I have set up everything as I want this includes several other view ports not showing the 3d object. my problem is that I can use the hide command in the view port containing the 3d object and get the image I want. However switching tabs or doing just about anything causes the 3d object in the view port to revert back to wire frame. Is there a way to lock just the one view port with hide mode on without effecting the rest of the view ports?